Therapy of chronic idiopathic thrombocytopenic purpura in adults.
نویسنده
چکیده
Results of different types of treatment in 416 adults with chronic idiopathic thrombocytopenic purpura (ITP) were analyzed. Of 368 patients treated with corticosteroids, 278 (77%) achieved complete response (CR ie, normalization of platelet count). However, only 18% of patients had continued complete response (CCR). Results of splenectomy was analyzed in 126 patients, 49% of them achieved CCR and 76% of them had beneficial effects from the operation. Emergency splenectomy was a life saving procedure in 8 of 11 patients with life-threatening hemorrhage. Vinca alkaloids gave a 50% transient CR. Immunosuppressive agents (cyclophosphamide, azathioprine) resulted in only 11% CCR.
منابع مشابه
Neutropenia Following Intravenous Immunoglobulin Therapy in Pediatric Patients with Idiopathic Thrombocytopenic Purpura
Background: Children with idiopathic thrombocytopenic purpura who are treated with intravenous immunoglobulin therapy might experience a decline in their absolute neutrophil count. The aim of this study was to investigate the incidence of neutropenia following intravenous immunoglobulin therapy in children with idiopathic thrombocytopenic purpura undergoing intravenous immunoglobulin therapy. ...
متن کاملRecovery of Thrombocytopenia after Eradica-tion of H. pylori Infection in Chronic Idiopathic Thrombocytopenic Purpura
Introduction: Recent studies have shown a relationship between H. pylori and chronic idiopathic thrombocytopenic purpura (CITP). Objective: The present study was performed to evaluate this relationship in Iranian patients. Methods: The antibody (IgG) against H. pylori was studied in sixty-two patients with CITP, comprising 25 males and 37 females (mean age: 30.38±12.23 yrs ) The patients posi...
متن کاملClinical Variables among Adult Patients with Chronic Idiopathic Thrombocytopenic Purpura in West Iran
Background: There are two forms of ITP: acute and chronic. The chronic form is defined by persistent thrombocytopenia for more than 12 months and mostly occurs among young women. The aim of the present study was to evaluate the clinical variables in adult patients with chronic ITP in West Iran. Patients and Methods: Between of 2007 and 2014, ninety adult patients with chronic ITP referred to...
متن کاملComparison of the Quality of Life among Patients with Idiopathic Thrombocytopenic Purpura and Healthy People in Isfahan, Iran
Background: Quality of life has been used as an important tool to understand illnesses impact in recent decades. Idiopathic thrombocytopenic purpura is a chronic disease which affects the individuals’ quality of life. The present study was conducted to compare the quality of life among idiopathic thrombocytopenic purpura patients’ with healthy people. Patients and Methods: This was a descri...
متن کاملAn Idiopathic Thrombocytopenic Purpura Patient Treated With Homeopathy: A Case Report
Introduction: Homeopathy can be applied to treat various diseases and conditions such as cancer, allergy, mood disorders, headache and pain. This case showed that homeopathic medicine can be a treatment modality for idiopathic thrombocytopenic purpura (ITP), an autoimmune-mediated hematologic disorder. Case Presentation: The patient was a 5.5–year-old child wi...
متن کاملEpidemiology of Idiopathic Thrombocytopenic Purpura in Children
Abstract Background Immune thrombocytopenic purpura (ITP) is a common autoimmune bleeding condition in children that is characterized by a decrease in the platelet count. The aims of this study were to define epidemiologic features of patients with primary ITP who were admitted to Mofid Children's Hospital, Tehran, Iran, in a 5-year period. Methods We retrospectively studied the records of ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Southeast Asian journal of tropical medicine and public health
دوره 24 Suppl 1 شماره
صفحات -
تاریخ انتشار 1982